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Date: 22 November 2009
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A genetic study reveals the diversity and origins of African populations  
Topic Name: A genetic study reveals the diversity and origins of African populations
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Category: Genetic Engineering

Research persons: Sarah Tishkoff

Location: Maryland, United States

Details

By analyzing the genetic differences between more than 3 000 people across Africa and from other parts of the world, researchers have shown how the current African populations had evolved from 14 aboriginal groups. The result of their research reveals an enormous genetic diversity throughout the continent and is also the foundation for future studies that may lead to important medical advances in Africa and a better understanding of the evolutionary history of human origins and its modern in Africa.

Sarah Tishkoff of the University of Maryland at College Park and a team of American researchers, Africa and Europe have studied the genetic variation among African populations 121, four African Americans and 60 non-African from DNA provided by volunteers and comparing the sequence of their genome for different genetic markers.

The researchers found a high mix of ancestors varied for most people that reflects their historical movements on the continent and describe their study in the key migration routes and evolutionary relationships key. In general, the table provided by the data genetic matches with what the researchers were able to reconstruct on the basis of cultural and linguistic types. It appears that populations of hunter-gatherers from various regions, including pygmies and the San whose language consists of clicks and other populations of East Africa also speaking with clicks, trace their ancestors common. African Americans are mainly from nigérokordofaniennes populations of West Africa (71 percent) and European as well (13 percent) and other parts of Africa (8 percent).

This study provides not only information on long evolutionary history of Africans and African Americans but also the foundation for many other lines of research. For example, it could help genetic epidemiologists to identify the most informative for making "case-control studies" to determine the genetic risk for certain diseases. It could also be used in pharmacogenomics researchers who want to know which ethnic groups should be included in their studies to optimize the performance of genetically diverse populations. Geneticists of the development could also use this data to answer such questions as when and where men have appeared in modern Africa and the size of the population has migrated out of Africa.


Tags: genetic difference - genetic diversity - genetic -
Research Documents:
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