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Topic Name: Discovery of a new protein involved in the occurrence of cardiovascular disease
Category: Biomedical
Research persons: Jacques Genest
Location: New England, Canada
Details
An international research team involving scientists from McGill University Health Center and McGill University, discovered a new protein to the onset of cardiovascular disease. Published in The New England Journal of Medicine, the results show that high protein hs-CRP (high-sensitivity C-reactive protein) results in a consequent risk of cardiovascular disease. The researchers also show that this risk can be reduced by treatment with statins.
"The risk of cardiovascular disease associated with high levels of hs-CRP was greatly underestimated until now. Our findings demonstrate that this is a very important indicator to be taken into account in the future "said Jacques Genest of the Research Institute of the McGill University Health Center.
The researchers in question are involved in the project JUPITER, which analyzed 17,802 patients in 27 countries. These patients had normal cholesterol levels and rate of hs-CRP high. They were not considered "at risk" according to current standards. During the study they received a daily dose of rosuvastatin, a drug class of statins. The consequences were conclusive: 44% reduced risk of cardiovascular disease, and 21% decrease of mortality.
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high-sensitivity C-reactive protein - - |
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