The new QNP CryoProbe, enables multipurpose NMR measurements of four different nuclei -- fluorine, phosphorus, carbon and hydrogen.  This unique 5mm, general-purpose, cryogenically cooled probe is automated to easily switch between these nuclei, eliminating the need to change probes.  Fluorine, phosphorus, carbon and hydrogen are present individually or together in a majority of organic, biological and inorganic compounds.  The direct observation of these nuclei can provide quantitative information in addition to small molecule structural data.  This new probe provides the CryoProbe equivalent of one of Bruker BioSpin’s most popular conventional probes.
 

The most significant advantage of this new probe is that it enables more complete characterization of molecules that contain any of these four nuclei.  The new QNP CryoProbe is available for Bruker BioSpin Avance 400 and 500 MHz NMR Spectrometer.
 
CryoProbes improve the signal-to-noise ratio by three to four times, as compared to non-cryogenically cooled probes.  As a result, they are capable of measuring lower concentrations and enable experiments to be completed as much as 16 times faster.  While traditional CryoProbes are aimed at biological research, this new QNP CryoProbe is designed for applications in organic and inorganic chemistry.